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ChemInform Abstract: 3-Chloro-4-fluorothiophene-1,1-dioxide. A New Synthetically Useful Fluorodiene.

โœ Scribed by W. DMOWSKI; V. MANKO; I. NOWAK

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
29
Category
Article
ISSN
0931-7597

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โœ K.-S. YEUNG; N. A. MEANWELL ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

A Synthesis of 4-Thiomethylbenzisothiazolone-1,1-dioxide Using HDPT. -The title compounds (V), required for pharmaceutical studies, are efficiently prepared starting with regioselective benzylic bromination of the corresponding dioxides (I). Coupling of the resulting benzyl bromides with HDPT (III)