✦ LIBER ✦

ChemInform Abstract: 3-Amino-2-piperidones as Constrained Pseudopeptides: Preparation of a New Ser-Leu Surrogate.

✍ Scribed by Jordi Piro; Mario Rubiralta; Ernest Giralt; Anna Diez

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199936228

No coin nor oath required. For personal study only.

✦ Synopsis

3-Amino-2-piperidones as Constrained Pseudopeptides: Preparation of a New Ser-Leu Surrogate. -A stereoselective synthesis of compound (VI), a new conformationally constrained Ser-Leu surrogate is described. Key steps are the lactamization of the aminolactone (II) and the regioselective introduction of azide into the cyclic sulfite (IV). -(PIRO, JORDI; RUBIRALTA,

📜 SIMILAR VOLUMES

ChemInform Abstract: A Short, Multigram

ChemInform Abstract: A Short, Multigram Synthetic Route to Methyl 2-Amino-4-methyl-3-thiophenecarboxylate as a Precursor for Preparation of New Biologically Active Derivatives and Novel Materials.

✍ R. PAVLOVICOVA; J. MINARIKOVA; D. HUDECOVA; D. VEGH 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

thiophenecarboxylate (III) and its conversion into novel ethylenic thiophenes (IX) is described. The antimicrobial activity of the prepared compounds is evaluated. Derivative (Va), the most active compound, shows remarkable antimicrobial activity on filamentous fungi.

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Effects of a New Series of 2-Amino-3-benzoylthiophenes as Allosteric Enhancers of A1-Adenosine Receptor.

✍ Pier Giovanni Baraldi; Abdel Naser Zaid; Ilaria Lampronti; Francesca Fruttarolo; 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

ChemInform Abstract: Design, Syntheses,

ChemInform Abstract: Design, Syntheses, and Activity of New 3-[(Sulfonylaryl)-amino]-1,4-benzodiazepin-2-one Derivatives as α-Thrombin Inhibitors.

✍ D. DUMAS; G. LECLERC; J. J. BALDWIN; S. D. LEWIS; M. MURCKO; A. M. NAYLOR-OLSEN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 41 KB 👁 1 views

ChemInform Abstract: Asymmetric Cyclopro

ChemInform Abstract: Asymmetric Cyclopropanation of Chiral (1-Dimethoxyphosphoryl-2-phenyl)vinyl p-Tolyl Sulfoxide: A New Synthesis of Enantiomerically Pure 2-Amino-3-phenyl-1-cyclopropane-phosphonic Acid — A Constrained Analogue of Phaclofen.

✍ Wanda H. Midura; Marian Mikolajczyk 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

ChemInform Abstract: (R)- and (S)-3-Hydr

ChemInform Abstract: (R)- and (S)-3-Hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone as Chiral Auxiliaries in the Enantioselective Preparation of α-Amino Acids.

✍ Pelayo Camps; Francesc Perez; Nuria Soldevilla; Miguel A. Borrego 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB 👁 1 views

ChemInform Abstract: Smiles Rearrangemen

ChemInform Abstract: Smiles Rearrangement as a Tool for the Preparation of 5-[(2-Hydroxyacyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamides: Main Pathway and Side Reactions.

✍ P. L. ANELLI; M. BROCCHETTA; L. CALABI; C. SECCHI; F. UGGERI; S. VERONA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 46 KB 👁 2 views