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ChemInform Abstract: 2- and 8-Functionalized 1,4,7,10-Tetraoxaspiro(5.5)undecanes. Part 3. Resolution of a (.+-.)-E,E Structure by Enzymatic and Chemical Methods.

✍ Scribed by M. LEMAIRE; G. JEMINET; J.-G. GOURCY; G. DAUPHIN


Book ID
112020495
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
26
Category
Article
ISSN
0931-7597

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2- and 8- functionalized 1,4,7,10-tetrao
✍ Marielle Lemaire; Georges Jeminet; Jean-Gabriel Gourcy; GΓ©rard Dauphin πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 448 KB

The optical resolution of a (f)-E,E-2,8-disubstituted-l,4,7,lO-tetraoxaspiro[5.5] undecane system was carried out by lipase-catalyzed hydrolysis of a symmetrical diester and also by monosubstitution with a chiral amine. Configurations of the new products were assigned by chemical correlations.