2- and 8- functionalized 1,4,7,10-tetrao
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Marielle Lemaire; Georges Jeminet; Jean-Gabriel Gourcy; GΓ©rard Dauphin
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Article
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1994
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Elsevier Science
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English
β 448 KB
The optical resolution of a (f)-E,E-2,8-disubstituted-l,4,7,lO-tetraoxaspiro[5.5] undecane system was carried out by lipase-catalyzed hydrolysis of a symmetrical diester and also by monosubstitution with a chiral amine. Configurations of the new products were assigned by chemical correlations.