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ChemInform Abstract: 17α-Alkyl- or 17α-Substituted Benzyl-17β-estradiols: A New Family of Estrone-Sulfatase Inhibitors.

✍ Scribed by D. POIRIER; R. P. BOIVIN


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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A Concise Route to 19-Nor-10-azasteroids, a New Class of Steroid 5α-Reductase Inhibitors. Part 3. Synthesis of (+)-19-Nor-10azatestosterone and (+)-17β-(Acetyloxy)-(5β)-10-azaestr-1-en-3-one. -The title compounds are of interest, since 5α-reductase inhibitors (by reducing the level of dihydrotesto