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ChemInform Abstract: 1,2,4-Triazines in Organic Synthesis. Part 4. Ring Opening and Ring Closure Reactions of 1,2,4-Triazines with Carbon Nucleophiles: A Novel Route to Functionalized 3-Aminopyridazines.

✍ Scribed by A. RYKOWSKI; E. WOLINSKA


Book ID
112040164
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
27
Category
Article
ISSN
0931-7597

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A new route to functionalized 3-aminopyr
✍ Andrzej Rykowski; Ewa Wolinska; Henk C. Van Der Plas πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 314 KB

## Abstract The reaction of 3‐chloro‐6‐phenyl‐1,2,4‐triazine **1a** with carbon nucleophiles **2aο£Ώd** bearing a cyano substituent at a carbanionic center has been studied. In all reactions the formation of the corresponding 3‐aminopyridazines **3aο£Ώd** takes place via ANRORC mechanism involving addi