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Ring opening and ring closure reactions of 1,2,4-triazines with carbon nucleophiles: A novel route to functionalized 3-aminopyridazines

✍ Scribed by Andrzej Rykowski; Ewa Woliñska


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
119 KB
Volume
37
Category
Article
ISSN
0040-4039

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A new route to functionalized 3-aminopyr
✍ Andrzej Rykowski; Ewa Wolinska; Henk C. Van Der Plas 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 314 KB

## Abstract The reaction of 3‐chloro‐6‐phenyl‐1,2,4‐triazine **1a** with carbon nucleophiles **2ad** bearing a cyano substituent at a carbanionic center has been studied. In all reactions the formation of the corresponding 3‐aminopyridazines **3ad** takes place via ANRORC mechanism involving addi