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Chemically modified cell-penetrating peptides for the delivery of nucleic acids

✍ Scribed by Mäe, Maarja; Andaloussi, Samir El; Lehto, Taavi; Langel, Ülo

Book ID: 120823542
Publisher: Informa plc
Year: 2009
Tongue: English
Weight: 576 KB
Volume: 6
Category: Article
ISSN: 1742-5247
DOI: 10.1517/17425240903213688

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Cell penetrating peptides (CPPs) are short amphipathic and cationic peptides that are rapidly internalized across cell membranes. They can be used to deliver molecular cargo, such as imaging agents (fluorescent dyes and quantum dots), drugs, liposomes, peptide/protein, oligonucleotide/DNA/RNA, nanop