Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells
β Scribed by Xiu Qin Xu; Ralph Graichen; Set Yen Soo; Thavamalar Balakrishnan; Siti Norfiza Bte Rahmat; Shirly Sieh; Su Chin Tham; Christian Freund; Jennifer Moore; Christine Mummery; Alan Colman; Robert Zweigerdt; Bruce P. Davidson
- Book ID
- 110914876
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 337 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0301-4681
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## Abstract Cardiovascular disease is one of leading causes of death throughout the U.S. and the world. The damage of cardiomyocytes resulting from ischemic injury is irreversible and leads to the development of progressive heart failure, which is characterized by the loss of functional cardiomyocy
The effects of electromagnetic fields (EMFs) on the differentiation of cardiomyocytes in embryoid bodies derived from pluripotent embryonic stem (ES) cells were investigated. A single direct current (DC) field pulse was applied to 4-day-old embryoid bodies. The electrical field induced a hyperpolari