Chemical transglycosylation of functional bioactive glyco-linkages

✍ Scribed by Tsuyoshi Ikeda; Tetsuya Kajimoto; Junei Kinjo; Kensei Nakayama; Toshihiro Nohara

• Book ID: 104259167
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 247 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00519-x

✦ Synopsis

The natural functional bioactive oligosaccharides moieties, mimosatetraose and fabatriose, were cut off from julibrosides and soyasaponin I by chemical and enzymatic methods, respectively, and were pasted to diosgenia to give neosaponins 1 and 2. The obtained neosaponins were tested for cytotoxicity and hepatoproteetive activity. This method could he applied to the synthesis of novel bioactive glycosides.