Chemical synthesis of L-[75Se]selenomethionine in a high-activity scale
✍ Scribed by Johannes Römer; Peter Mäding; Frank Rösch
- Book ID
- 103922857
- Publisher
- Elsevier Science
- Year
- 1992
- Weight
- 509 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0883-2889
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A fast chemical synthesis of high specific activity [75Se]L-selenomethionine (10 Ci/mmol--370 GBq/mmol) is described with a view to 73Se labeling and PET studies. The overall radiochemical yield of the preparation is better than 80%. The purification method uses commercially available reverse phase
A modification of Brook's prelabeling (7sSE) selenomethionine assay was developed and evaluated for detection of complement-dependent antibody (CDA) in a human tumor system. CDA was indeed detected in some breast cancer patients' sera. To determine whether the assay was reliable and reproducible, xe