A convenient synthesis of 2′-deoxyribonu
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Bozenna K. Krzyzanowska; Kaizhang He; Ahmad Hasan; Barbara Ramsay Shaw
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Article
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1998
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Elsevier Science
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French
⚖ 556 KB
A new class of nucleotides, with one of the two non-bridging oxygens at or-phosphorus replaced by a borane (BH3) group, has shown potential applications in DNA sequencing. We have developed a convenient method for the synthesis of the 2'-deoxy-5'-(ot-P-borano)triphosphates of adenosine, guanosine, c