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Chemical synthesis of 32P glycosyl phosphates

โœ Scribed by W.A. Khan; K.E. Ebner

Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
271 KB
Volume
22
Category
Article
ISSN
0003-2697

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๐Ÿ“œ SIMILAR VOLUMES

A new chemical method of synthesis of mo
A new chemical method of synthesis of modified nucleoside [32P]phosphates
โœ D. V. Yanvarev; E. A. Shirokova; M. K. Kukhanova; Yu. S. Skoblov ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 131 KB

## Abstract A simple method of chemical phosphorylation for modified nucleosides with [^32^P]orthophosphoric acid in the presence of BrCN is described. The yields of 5โ€ฒโ€[^32^P]nucleoside monophosphates achieved are 50โ€“65% at nominal specific radioactivities of ca. 1000โ€‰Ci/mmol. The mechanism of pho