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Chemical Synthesis, Cloning, and Expression of Genes for Human Somatomedin C (Insulin-like Growth Factor I) and 59Val-Somatomedin C

โœ Scribed by MINEO NIWA; SUSUMU SATO; YOSHIMASA SAITO; FUMIAKI UCHIYAMA; HIROKI ONO; MITSUO YAMASHITA; TADASHI KITAGUCHI; YUMIKO SHIGA; JOJI NOTANI; HISASHI YAMADA; YOSHINORI ISHII; IKUO UEDA; YASUYUKI TAKAGI


Book ID
118723583
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
1011 KB
Volume
469
Category
Article
ISSN
0890-6564

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Insulin-like growth factor I/somatomedin
โœ Cheryl A. Conover; Laura A. Dollar; Raymond L. Hintz; Ron G. Rosenfeld ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 739 KB

In serum-free medium, insulin-like growth factor-lisomatomedin-C (IGWSM-C) was weakly mitogenic for adult human fibroblasts in culture. However, in the presence of 0.5% h u m a n hypopituitary serum (HHS), which by itself had little effect, there was a marked dose-dependent response to IGF-IISM-C wi