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Chemical synthesis and molecular pharmacology of hydroxylated 1-(1-phenylcyclohexyl)piperidine derivatives

✍ Scribed by Kamenka, J. M.; Chiche, B.; Goudal, R.; Geneste, P.; Vignon, J.; Vincent, J. P.; Lazdunski, M.


Book ID
115481737
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
692 KB
Volume
25
Category
Article
ISSN
0022-2623

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## Abstract The synthesis of high specific activity tritium labelled 4‐isothiocyanato‐1‐(1‐phenylcyclohexyl)piperidine ([^3^H]fourphit), a probe for the autoradiographic study of the dopamine reuptake complex, is described. An improved, facile synthesis of unlabelled fourphit in high overall yield