In aqueous solution, melittin structure, investigated by CD and 'H-nmr, depends on pH and ionic composition, which also regulate the aggregation state of the peptide. When interacting with phospholipids, however, melittin exhibits a right-handed helical conformation without any evidence of oligomeri
Chemical Structure and Biological Action of the Components of Bee Venom
β Scribed by Prof. Dr. E. Habermann
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 231 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0044-8249
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π SIMILAR VOLUMES
**Potential value in the therapy of rheumatism and other inflammation processes** could attach to the MCD peptide from bee venom if it were available in larger quantities. The peptide consists of 22 amino acids and contains two disulfide bridges. Its first total synthesis has now been accomplished.
The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybee (Apis mellifera) venom, both collected in the State of SΓ£o Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct-and indirect-acting mutagens. EEP had inhibitory effect (in an ascending order) on the mut