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Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

✍ Scribed by Eliana Ap. Varanda; Rubens Monti; Denise C. Tavares

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 94 KB
Volume: 19
Category: Article
ISSN: 0270-3211
DOI: 10.1002/(sici)1520-6866(1999)19:6<403::aid-tcm4>3.0.co;2-2

No coin nor oath required. For personal study only.

✦ Synopsis

The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybee (Apis mellifera) venom, both collected in the State of São Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct-and indirect-acting mutagens. EEP had inhibitory effect (in an ascending order) on the mutagenicity power of daunomycin (TA102), benzo(a)pyrene (TA100), and aflatoxin B 1 (TA98) and the venom acted against the mutagenicity of 4-nitro-o-phenylenediamine (TA98) and daunomycin (TA102).

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