β Scribed by Benjamin F Cravatt; Erik J Sorensen
No coin nor oath required. For personal study only.
As the human genome project nears completion, biological research is entering a new era in which experimental focus will shift from identifying novel genes to determining the function of gene products. Rising to this challenge, several technologies have emerged that aim to characterise genes and/or proteins collectively rather than individually. Of particular interest is a new breed of strategies that employs synthetic chemistry to enrich our understanding of protein function on a global scale.
π SIMILAR VOLUMES
## Abstract The chemical activation of biological proteins is outlined, in which small molecules are used to alter the chemical and physical properties of biological proteins through direct or indirect interactions. Crown ethers have the potential to modulate the protein functions by supramolecular
## Abstract The advent of high throughput gene expression profiling, from microarrays to sequence based assays has yielded vast insight into the biology of tumors. New technologies are constantly being unveiled which promise to generate more accurate maps of tumor gene deregulation, and demand the
## Abstract Among postβtranslational modifications of proteins, nonβenzymatic glycation is one of the less frequently studied by experts in proteomics. However, the relevance of protein glycation has been widely shown up in several pathological conditions. In fact, nonβenzymatic glycation has been