✦ LIBER ✦

Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor1 receptor antagonists: Aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d]pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives

✍ Scribed by Toshihito Kumagai; Taketoshi Okubo; Hiromi Kataoka-Okubo; Shigeyuki Chaki; Shigeru Okuyama; Atsuro Nakazato

Book ID: 108479048
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 160 KB
Volume: 9
Category: Article
ISSN: 0968-0896
DOI: 10.1016/s0968-0896(01)00005-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Antiviral and Antitumor Ac

Synthesis and Antiviral and Antitumor Activities of 2H-[1,2,3]Triazolo[4,5-d]pyrimidines and 1H-, 2H-, and 3H-[1,2,3]Triazolo[4,5-d]pyrimidin-5(4H)-one-7(6H)-thiones.

✍ Rafiqul Islam; Tomohisa Nagamatsu 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Heteroaryl-Substituted 4-(1H-pyrazol-1-y

Heteroaryl-Substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine Derivatives as Potent and Selective Corticotropin-Releasing Factor Receptor-1 Antagonists

✍ Fabio Maria Sabbatini; Romano Di Fabio; Yves St-Denis; Anna-Maria Capelli; Emili 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 1 views

ChemInform Abstract: Utility of Cyanoace

ChemInform Abstract: Utility of Cyanoacetamides as Precursors to Pyrazolo[3,4-d]pyrimidin-4-ones, 2-Aryl-6-substituted 1,2,3-Triazolo[4,5-d]pyrimidines and Pyrazolo[1,5-a]pyrimidine-3-carboxamides.

✍ Hamada Mohamed Ibrahim; Saad Makhseed; Ramadan Maawad Abdel-Motaleb; Abdel-Monei 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 43 KB 👁 1 views

Synthesis of [3H]-labelled 4-[Ethyl[2,5,

Synthesis of [3H]-labelled 4-[Ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3-[3H]-butan-1-ol: a high affinity radioligand for the corticotropin-releasing hormone type 1 receptor

✍ Anne-Cécile Hiebel; John S. Partilla; Richard B. Rothman; Arthur E. Jacobson; Ke 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 117 KB

3 H]-Labelled 4- [ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3-[ 3 H]-butan-1-ol (3b) was prepared as a novel non-peptidic radiolabelled high affinity antagonist of the corticotropin-releasing hormone type 1 receptor (CRHR 1 ) that could be useful as a more

ChemInform Abstract: Design, Synthesis a

ChemInform Abstract: Design, Synthesis and Evaluation of Antitumor and Antiviral Activities of 5-Amino-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones (8-Azaguanines) and 7-Amino-1H-[1,2,3]triazolo[4,5-d]pyrimidin-5(4H)-ones (8-Azaisoguanines).

✍ Rafiqul Islam; Noriyuki Ashida; Tomohisa Nagamatsu 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

ChemInform Abstract: Utility of 2-Amino-

ChemInform Abstract: Utility of 2-Amino-4,5,6,8-tetrahydro-7H-chromene-3-carbonitriles in Synthesis of Chromeno[2,3-d]pyrimidine and Chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives of Pharmaceutical Interest.

✍ A. A. Hassanien; M. A. Zahran; M. S. A. El-Gaby; M. M. Ghorab 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views