Chemical-inducible expression systems, or "gene switchesΓ, provide an opportunity for the temporal, spatial and quantitative control of genetically engineered traits. This review describes molecular and chemical aspects of several gene switches which have appeared in the literature and a novel unpub
Chemical-inducible systems for regulated expression of plant genes
β Scribed by Jianru Zuo; Nam-Hai Chua
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 84 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0958-1669
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β¦ Synopsis
Chemical regulation of transgene expression presents a powerful tool for basic research in plant biology and biotechnological applications. Various chemical-inducible systems based on de-repression, activation and inactivation of the target gene have been described. The utility of inducible promoters has been successfully demonstrated by the development of a marker-free transformation system and largescale gene profiling. In addition, field applications appear to be promising through the use of registered agrochemicals (e.g. RH5992) as inducers.
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