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Chemical impurities in [18F]FDG preparations produced by solid-phase 18F-fluorination

✍ Scribed by Yuji Kuge; Ken-ichi Nishijima; Kotaro Nagatsu; Koh-ichi Seki; Kazue Ohkura; Akira Tanaka; Motoji Sasaki; Eriko Tsukamoto; Nagara Tamaki

Book ID
117687797
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
78 KB
Volume
29
Category
Article
ISSN
0969-8051

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## Abstract The synthesis of 2‐deoxy‐2‐[^18^F]fluoro‐D‐glucose ([^18^F]FDG) has been simplified by the use of a ^t^C18 Sep Pak cartridge to effect purification and hydrolysis of the tetraacetylated [^18^F]fluoro‐glucose compound ([^18^F]TAG). After radiolabelling, this derivative was trapped on a s