Chemical characteristics of 99mTc-labeled amine phenols

✍ Scribed by Jem-Mau Lo; Kuo-Shyan Lin; Chuarn-Yuh Huang

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 627 KB
• Volume: 45
• Category: Article
• ISSN: 0969-8043
• DOI: 10.1016/0969-8043(94)90202-x

✦ Synopsis

A series of alkylene amine phenols including En(AP),, Pn(AP),, DmPn(AP),, Bn(AP), and Pent(AP),, were synthesized and complexations of the amine phenols with a trace-level 99mTc0; were undertaken in the presence of St*+. The %Tc-amine phenol complexes obtained were characterized simultaneously by solvent extraction, TLC, electrophoresis and HPLC. The labeling yield, neutrality, lipophilicity and stability of the %Tc-amine phenol complexes were sufficiently investigated. The chemical behaviors of the complexes of no-carrier-added %Tc with the amine phenols found in observed study are related to the lengths of hydrocarbon backbones of the ligands.