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Chemical and Chemoenzymatic Synthesis of Nucleoside 5′-α-Thiotriphosphates

✍ Scribed by K. V. Antonov; R. S. Esipov; A. I. Gurevich; D. V. Chuvikovsky; G. V. Mikulinskaya; S. A. Feofanov; A. I. Miroshnikov


Book ID
111607341
Publisher
SP MAIK Nauka/Interperiodica
Year
2003
Tongue
English
Weight
97 KB
Volume
29
Category
Article
ISSN
1068-1620

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Enzymatic Synthesis of Nucleoside-5′-O-(
✍ Vladimir N. Barai; Anatoli I. Zinchenko; Sergei V. Kvach; Olga I. Titovich; Elen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 92 KB

## Abstract Treatment of adenosine with PSCl~3~ in trimethyl phosphate gave, after ion‐exchange chromatography, adenosine‐5′‐__O__‐monophosphate (AMP; 28%) and adenosine‐5′‐__O__‐monothiophosphate (AMPS; 48%). AMPS was studied as a thiophosphate residue donor in an enzymatic transphosphorylation wi