𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Chemical Analysis of Solid-State Irradiated Human Insulin

✍ Scribed by Hélène Terryn; Jean-Paul Vanhelleputte; Aubert Maquille; Bernard Tilquin


Book ID
106492868
Publisher
Springer US
Year
2006
Tongue
English
Weight
507 KB
Volume
23
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Analysis of insulin allostery in solutio
✍ Morten Jonas Maltesen; Simon Bjerregaard; Lars Hovgaard; Svend Havelund; Marco v 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB

The insulin hexamer acts as an allosteric unit mediated by homotropic and heterotropic effects shifting the equilibrium between three distinct conformational states (T 6 , R 3 T 3 and R 6 ). The homotropic ligand phenol stabilises the R 6 state by binding to hydrophobic pockets only present in the R