Inactivation of the human retinoblastoma tumor-suppressor gene (RB1; MIM # 180200) is usually caused by mutations in the coding region, but mutations in the promoter region can also affect RB1 gene expression. A 103-bp deletion in the promoter region in a prostate cancer was reported to abrogate RB1
Characterization of three new VNTR alleles in the promoter region of the TPMT gene
✍ Scribed by Sandra Alves; Fátima Ferreira; Maria João Prata; António Amorim
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 14 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1059-7794
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✦ Synopsis
VNTR*3 (new) -act(gaggcggggcgcgggaaa) 1 (gaggcggggcgcgggcg) 1 (gaggcggggcgcggaga) 1 agt VNTR*4 -act(gaggcggggcgcgggaaa) 2 (gaggcggggcgcgggcg) 1 (gaggcggggcgcggaga) 1 agt VNTR*4b (new) -act(gaggcggggcgcgggaaa) 1 (gaggcggggcgcgggcg) 2 (gaggcggggcgcggaga) 1 agt VNTR*6 -act(gaggcggggcgcgggaaa) 2 (gaggcggggcgcgggcg) 3 (gaggcggggcgcggaga) 1 agt VNTR*6b (new) -act(gaggcggggcgcgggaaa) 1 (gaggcggggcgcgggcg) 4 (gaggcggggcgcggaga)
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