Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: Effect of cellular differentiation
β Scribed by Anna R. Giuliano; Renny T. Franceschi; Richard J. Wood
- Book ID
- 115708876
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 963 KB
- Volume
- 285
- Category
- Article
- ISSN
- 0003-9861
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The transepithelial absorption of food-type proteins has been shown to proceed by endocytosis along two functional pathways: a minor direct pathway allowing transport of intact protein and J major lysosomal degradative pathway. The human colon carcinoma cell line CaCo-2 grown on Millipore filters wa
## Abstract We examined the effects of 1,25 dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) on the distribution and mobility of the vitamin D receptor (VDR) in the enterocyteβlike Cacoβ2 cell. Confocal microscopy showed that a green fluorescent proteinβvitamin D receptor (GFPβVDR) fusion protein is predomi