𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of the Regional Intestinal Kinetics of Drug Efflux in Rat and Human Intestine and in Caco-2 Cells

✍ Scribed by Vijaya D. Makhey; Ailan Guo; Daniel A. Norris; Peidi Hu; Jiansheng Yan; Patrick J. Sinko

Book ID
110308124
Publisher
Springer US
Year
1998
Tongue
English
Weight
693 KB
Volume
15
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Transport of levovirin prodrugs in the h
Transport of levovirin prodrugs in the human intestinal Caco-2 cell line
✍ Fujun Li; Lei Hong; Cheng-I Mau; Rebecca Chan; Than Hendricks; Chuck Dvorak; Cal πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 142 KB πŸ‘ 1 views

The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi