𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of the receptor mediating the nicotine discriminative stimulus

✍ Scribed by Carmelo Romano; Avram Goldstein; Nicholas P. Jewell

Publisher
Springer
Year
1981
Tongue
English
Weight
663 KB
Volume
74
Category
Article
ISSN
0033-3158

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Discriminative stimulus properties of ni
Discriminative stimulus properties of nicotine: Further evidence for mediation at a cholinergic receptor
✍ J. A. Pratt; I. P. Stolerman; H. S. Garcha; V. Giardini; C. Feyerabend πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 800 KB

Rats were trained to discriminate nicotine (0.4 mg/kg SC) from saline in a standard two-bar operant conditioning procedure with food reinforcement. The response to nicotine was dose-related and at the ED50 of 0.14 mg/kg, plasma nicotine concentrations were similar to those reported previously for ci

Discriminative stimulus properties of ni
Discriminative stimulus properties of nicotine: Approaches to evaluating potential nicotinic receptor agonists and antagonists
✍ Jenny L. Wiley; John R. James; John A. Rosecrans πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 863 KB

The prototypic nicotinic acetylcholinergic receptor (nAChR) agonist, nicotine, is one of the primary psychoactive ingredients of tobacco. This review examines the effects of nicotine and similar compounds in nicotine discrimination procedures, a paradigm in which the subjective effects of nicotine c

Modulation of the discriminative stimulu
Modulation of the discriminative stimulus properties of (βˆ’)-nicotine by diazepam and ethanol
✍ David J. B. Kim; Jorge D. Brioni πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 669 KB

## Abstract The effect of different ligands for the GABA‐BZD receptor and the NMDA receptor were studied in rats trained to discriminate (βˆ’)‐nicotine (1.9 ΞΌmol/kg) from saline in a standard two‐bar operant conditioning paradigm with food reinforcement. MK‐801 (0.03–0.3 ΞΌmol/kg), flumazenil (10–30 ΞΌ