Characterization of the protein tyrosine phosphatase CD45 on human epidermal Langerhans cells
✍ Scribed by Thomas Bieber; Maren Jürgens; Andreas Wollenberg; Erika Sander; Daniel Hanau; Henri de la Salle
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 517 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A simple, high-throughput fluorescent assay was developed to measure the inhibition of membrane-bound CD45 from Jurkat cells. This assay is based on the fact that ϳ64% of PTP activity from Jurkat cell membrane is contributed by CD45. This has been proven by comparing the activity in membrane protein
## Abstract Recently, we reported that Src homology 2 domain‐containing protein tyrosine phosphatase substrate 1 (SHPS‐1) plays an important role in the migration of Langerhans cells (LC). Here, we show that SHPS‐1 is involved in the maturation of LC. Immunofluorescence analysis on epidermal sheets