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Characterization of the Nef protein in HIV1-infected CEM cells

✍ Scribed by Laurent-Crawford, A.G.; Hovanessian, A.G.

Book ID
123525227
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
352 KB
Volume
143
Category
Article
ISSN
0923-2516

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Nef is a multifunctional gene of HIV which can increase virus replication either directly or by modulating the target cell's metabolism. Nevertheless the role of the exogenous Nef protein is not yet well understood. To investigate it, we studied the eects of the recombinant Nef protein on the expres