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Characterization of the intermediate filament apparatus in skin fibroblasts from patients with giant axonal neuropathy: Effect of trypsin

✍ Scribed by Manetti, Roberto ;Ceccarini, Constante ;Guazzi, Giancarlo ;Federico, Antonio ;Tiezzi, Antonio ;Bugnoli, Massimo ;Ceccarini, Elvira Costantino

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 561 KB
Volume: 8
Category: Article
ISSN: 0886-1544
DOI: 10.1002/cm.970080108

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✍ Ivleva Tatiana; Wiederschain German 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 802 KB

## ABSTRACT Immunofluorescence microscopy shows that unlike cytoplasmic microtubules (MT), vimentin‐type intermediate filaments (IF) are collected into ring‐shaped structures in affected fibroblasts. The altered IF organization could be observed in monolayers of polarized fibroblasts in the prolong