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Characterization of the Dynamic Structural Changes of Melittin - Lipid Bilayer Interactions

✍ Scribed by Devi, Usha; Gostock, Mark; Popplewell, Jonathan F.; Swann, Marcus J.

Book ID
119205316
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
36 KB
Volume
96
Category
Article
ISSN
0006-3495

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Adsorption of melittin to a lipid bilaye
Adsorption of melittin to a lipid bilayer : A molecular dynamics study
✍ J.-H. Lin; A. BaumgΓ€rtner πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 349 KB

Molecular dynamics simulations of melittin at high dilution near a fully hydrated bilayer membrane composed ofPOPC lipids have been performed for a total time of 1.36 ns. It is shown that melittin adsorbs to the membrane. In the adsorbed state the protein exhibits a well defined conformation and ori