✦ LIBER ✦

Characterization of the cardiac phenotype in neonatal Ts65Dn mice

✍ Scribed by Austin D. Williams; Corey H. Mjaatvedt; Clara S. Moore

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 367 KB
Volume: 237
Category: Article
ISSN: 1058-8388
DOI: 10.1002/dvdy.21416

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Parallels of craniofacial maldevelopment

Parallels of craniofacial maldevelopment in down syndrome and Ts65Dn mice

✍ Joan T. Richtsmeier; Laura L. Baxter; Roger H. Reeves 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB 👁 1 views

Mouse genetic models can be used to dissect molecular mechanisms that result in human disease. This approach requires detection and demonstration of compelling parallels between phenotypes in mouse and human. Ts65Dn mice are at dosage imbalance for many of the same genes duplicated in trisomy 21 or

Synaptic structural abnormalities in the

Synaptic structural abnormalities in the Ts65Dn mouse model of down syndrome

✍ Pavel V. Belichenko; Eliezer Masliah; Alexander M. Kleschevnikov; Angela J. Vill 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 992 KB

Differentiation of the dopaminergic phen

Differentiation of the dopaminergic phenotype in the olfactory system of neonatal and adult mice

✍ Sachiko Saino-Saito; Hayato Sasaki; Bruce T. Volpe; Kazuto Kobayashi; Roseann Be 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 721 KB

Cell cycle alteration and decreased cell

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with down syndrome and in Ts65Dn mice

✍ Andrea Contestabile; Tatiana Fila; Claudio Ceccarelli; Paola Bonasoni; Laura Bon 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 745 KB

## Abstract Down syndrome (DS), the leading genetic cause of mental retardation, is characterized by reduced number of cortical neurons and brain size. The occurrence of these defects starting from early life stages points at altered developmental neurogenesis as their major determinant. The goal o

Reduced phospholipase C-β activity and i

Reduced phospholipase C-β activity and isoform expression in the cerebellum of TS65DN mouse: A model of down syndrome

✍ Iñigo Ruiz de Azúa; María Ángeles Lumbreras; Amaia Zalduegui; Carmela Baamonde; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract Agonist‐ and guanine‐nucleotide‐stimulated phospholipase C‐β (PLC) activity was characterized in crude plasma membrane preparations from cerebral cortex, hippocampus and cerebellum of Ts65Dn mice, a model for Down syndrome, and their control littermates. The levels of expression of PLC‐

Electrocardiographic findings in mdx mic

Electrocardiographic findings in mdx mice: A cardiac phenotype of Duchenne muscular dystrophy

✍ Victor Chu; Jose M. Otero; Orlando Lopez; Matthew F. Sullivan; James P. Morgan; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB