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Characterization of the blast cell population in two neonates with Down's syndrome and transient myeloproliferative disorder

โœ Scribed by L. Coulombel; M. Derycke; J. L. Villeval; C. Leonard; J. Breton-Gorius; M. Vial; P. Bourgeois; G. Tchernia


Book ID
114711270
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
953 KB
Volume
66
Category
Article
ISSN
0007-1048

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Transient myeloproliferative disorder (TMD) in neonates with Down syndrome is characterized by increased megakaryoblastic cells in the peripheral blood. Despite their spontaneous regression in weeks, prognosis is not always favorable because of fatal hepatic fibrosis. In this study, blood thrombopoi