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Characterization of the Binding Properties and Retrograde Axonal Transport of a Monoclonal Antibody Directed against the Rat Nerve Growth Factor Receptor

✍ Scribed by Megumi Taniuchi and Eugene M. Johnson, Jr.


Book ID
124787744
Publisher
Rockefeller University Press.
Year
1985
Tongue
English
Weight
563 KB
Volume
101
Category
Article
ISSN
0021-9525

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Spleen cells from BALB/c mice immunized with a plasma membrane-enriched fraction from rabbit sympathetic ganglia were Sused with the mouse myeloma NS 1. A hybrid clone was obtained that produced monoclonal antibody directed against the receptor for nerve growth factor (NGF). The antibody, identified