Characterization of the antigenicity of the formiminotransferase-cyclodeaminase in type 2 autoimmune hepatitis
β Scribed by Reginald Renous; Pascal Lapierre; Idriss Djilali-Saiah; Susana Vitozzi; Fernando Alvarez
- Book ID
- 116980835
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 394 KB
- Volume
- 292
- Category
- Article
- ISSN
- 0014-4827
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The occurrence of anti-neutrophil cytoplasmic antibodies (ANCA) has been described in sera of patients with autoimmune hepatitis (AIH). The significance of this finding remains uncertain and the nature of the target antigen(s) has not yet been defined. We studied 32 sera from patients with AIH type
Autoimmune hepatitis (AIH) is characterized by an immune-mediated injury of the hepatic parenchyma of unknown pathogenesis. Type 2 AIH is identified by the presence of antiliver-kidney microsomes type 1 (anti-LKM1) and anti-liver cytosol type 1 (anti-LC1) autoantibodies. The current study shows that