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Characterization of the Activation of Na+/H+Exchange in Lymphocytes by Phorbol Esters: Change in Cytoplasmic pH Dependence of the Antiport

โœ Scribed by S. Grinstein, S. Cohen, J. D. Goetz, A. Rothstein and E. W. Gelfand


Book ID
123631785
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
879 KB
Volume
82
Category
Article
ISSN
0027-8424

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Activation of the Na+/H+ exchanger by ph
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Activation of neutrophils leading to superoxide production is accompanied by cytoplasmic alkalinization, which results from stimulation of the Na+/H+ exchanger. Since the exchanger undergoes permanent alterations during neutrophilic maturation of HL-60 cells (Costa-Casnellie et al.: Journal of Biolo