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Characterization of the activation function-2 domain of the human 1,25-dihydroxyvitamin D3 receptor

✍ Scribed by Shigeo Nakajima; Masayo Yamagata; Norio Sakai; Keiichi Ozono

Book ID
117463975
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
320 KB
Volume
139
Category
Article
ISSN
0303-7207

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## Abstract Treatment with 10^βˆ’8^ m 1,25‐dihydroxyvitamin D~3~ for 24 h causes transcriptional activation of the human insulin receptor gene in U‐937 human promonocytic cells. The activation seems to potentiate the response to insulin in terms of glucose oxidation. Wortmannin, a phosphatidylinosito