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Characterization of the acetaminophen-glutathione conjugation reaction by liver microsomes: Species difference in the effects of acetone

✍ Scribed by Liu, Jian; Sato, Chifumi; Marumo, Fumiaki

Book ID
121903081
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
380 KB
Volume
56
Category
Article
ISSN
0378-4274

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## Abstract An assay based on microbore liquid chromatography–positive ion electrospray mass spectrometry with selected ion recording has been developed for the measurement of the glutathione conjugate of paracetamol (acetaminophen) in human hepatic microsomal incubations. A deuterated analogue of