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Characterization of stereospecific binding of 3H-(-)sulpiride, a selective antagonist at dopamine-D2 receptors, in rat CNS

✍ Scribed by M. Memo; S. Govoni; E. Carboni; M. Trabucchi; P.F. Spano

Book ID
114075150
Publisher
Elsevier Science
Year
1983
Weight
459 KB
Volume
15
Category
Article
ISSN
0031-6989

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A novel benzazepine, SCH 23390, has recently been described as a very potent and selective dopamine D-1 receptor antagonist based on its potent inhibition of dopamine sensitive adenylate cyclase and its selective displacement of 3H-piflutixol from rat striatal receptor sites. In the present study, t