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Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2

✍ Scribed by Kosuke Nishi; Huazhang Huang; Shizuo G. Kamita; In-Hae Kim; Christophe Morisseau; Bruce D. Hammock


Book ID
116177504
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
426 KB
Volume
445
Category
Article
ISSN
0003-9861

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✍ Wiersma, David A. ;Schnellmann, Rick G. ;Sipes, I. Glenn πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

The nematocide, grain fumigant, and gasoline additive 1,2-dibromoethane (DBE) is both a cellular and a genetic toxin that is metabolically activated in rats and mice by mixed function oxidases (MFO) as well as glutathione S-transferases (GST). The purpose of this study was to determine whether DBE i