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Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor

โœ Scribed by Williams, Keith; Dawson, Valina L.; Romano, Carmelo; Dichter, Marc A.; Molinoff, Perry B.


Book ID
120998043
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
990 KB
Volume
5
Category
Article
ISSN
0896-6273

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Inverse Agonists at the Polyamine-Sensitive Modulatory Site of the NMDA Receptor: 50-Fold Increase in Potency by Insertion of an Aromatic Ring into an Alkanediamine Chain. -Among the products synthesized derivative (Ic) represents the most potent polyamine inverse agonist presently known. It inhibit