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Characterization of peroxisome proliferator-activated receptor alpha in normal rat mammary gland and 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary gland tumors from rats fed high and low fat diets

✍ Scribed by Sarah J Roberts-Thomson; Elizabeth G Snyderwine


Book ID
119536917
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
290 KB
Volume
118
Category
Article
ISSN
0378-4274

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Activating mutations in and expression of the Ha-ras gene were examined in benign and malignant female Sprague-Dawley rat mammary gland tumors induced by the heterocyclic amine 2-amino-1-methyl-6phenylimidazo[4,5-b]pyridine (PhIP) and promoted by a diet high in polyunsaturated fat. Ha-ras mutations