Mass spectrometry-based techniques continue to undergo active development for applications to nucleic acids, fueled by methods based on electrospray and matrix-assisted laser desorption ionization. In the past two years, notable advances have occurred in multiple interrelated areas, including sequen
Characterization of oligonucleotides and nucleic acids by mass spectrometry
โ Scribed by Patrick A Limbach; Pamela F Crain; James A McCloskey
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 858 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract | I. | Introduction | 311 | | | A. Nucleic Acid Structures and Properties | 311 | | | B. Principles of LC of Nucleic Acids | 312 | | | โโ1. ReversedโPhase HPLC | 312 | | | โโ2. IonโPair ReversedโPhase HPLC | 314 | | | โโ3. Affinity Chromatography | 314 | | | C. Principles of ESI M
The products of the reaction of the antitumor drug cisplatin (cis-diamminedichloroplatinum(II)) with four oligonucleotide tetramers, d(GpCpGpC), d(GpGpCpC), d(TpGpApT), and d(TpGpCpT), were separated by gel permeation chromatography and characterized by negative- and positive-ion fast atom bombardme