Induction of neuronal nitric oxide synth
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Masayuki Ikeda; Hiroshi Komachi; Ikuko Sato; Toshiyuki Himi; Tatsuhiko Yuasa; Se
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Article
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1999
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John Wiley and Sons
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English
β 42 KB
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A free radical, nitric oxide (NO), besides being a messenger molecule in the brain, becomes a neurotoxin if overproduced. We recently reported that methylmercury (MeHg) induces neuronal NO synthase (nNOS) in Purkinje cells. In the present study, we examined the distribution and the mechanism of nNOS