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Characterization of Neutral and Acidic Glycosphingolipids in Brains of Two Patients with GM1 Gangliosidosis Type 1 and Type 2

✍ Scribed by Yukitoshi Ishikawa; Akira Makita; Ryoji Minami

Book ID
111173449
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
785 KB
Volume
44
Category
Article
ISSN
0022-3042

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GM1-gangliosidosis: Accumulation of gang
GM1-gangliosidosis: Accumulation of ganglioside GM1in cultured skin fibroblasts and correlation with clinical types
✍ Yoshiyuki Suzuki; Norimasa Nakamura; Kazuko Fukuoka πŸ“‚ Article πŸ“… 1978 πŸ› Springer 🌐 English βš– 270 KB

Uptake of radioactivity from 14C-galactose into gangliosides by cultured skin fibroblasts was studied. GM3 was the major ganglioside in control human fibroblasts. An increase of GM1 was demonstrated in GM1-gangliosidosis fibroblasts. The degree of GM1 accumulation was correlated with the clinical ty