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Characterization of NADPH-cytochrome P-450 reductase in a mouse hepatoma cell line

✍ Scribed by Duthu, Gwen S.; Nestor, Mark S.; Berliner, Judith A.; Philpot, Richard M.; Hankinson, Oliver

Book ID
123375726
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
901 KB
Volume
18
Category
Article
ISSN
0304-3835

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## Abstract Summary: NADPH‐cytochrome P450 reductase (CPR or POR) is the obligatory electron donor for all microsomal cytochrome P450 (CYP or P450)‐catalyzed monooxygenase reactions. Disruption of the mouse __Cpr__ gene has been reported to cause prenatal developmental defects and embryonic lethali