𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of Multiple Stable Conformers of the EC5 Domain of E-cadherin and the Interaction of EC5 with E-cadherin Peptides

✍ Scribed by Kai Zheng; Jennifer S. Laurence; Krzysztof Kuczera; Gennady Verkhivker; C. Russell Middaugh; Teruna J. Siahaan

Book ID
111368694
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
829 KB
Volume
73
Category
Article
ISSN
1747-0277

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Evaluation of the physical stability of
Evaluation of the physical stability of the EC5 domain of E-cadherin: Effects of pH, temperature, ionic strength, and disulfide bonds
✍ Kai Zheng; C. Russell Middaugh; Teruna J. Siahaan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 472 KB

The development of protein drugs has been hampered by difficulties in formulating them due to their inherent chemical and physical stability, which could generate problems during the late stages of development. Thus, a basic understanding of the effect of structural features on the physicochemical s

The role of covalent dimerization on the
The role of covalent dimerization on the physical and chemical stability of the EC1 domain of human E-cadherin
✍ Maulik Trivedi; R. Andrew Davis; Yumna Shabaik; Ambrish Roy; Gennady Verkhivker; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 729 KB

The objective of this work was to evaluate the solution stability of the EC1 domain of E-cadherin under various conditions. The EC1 domain was incubated at various temperatures (4, 37, and 70 degrees C) and pH values (3.0, 7.0, and 9.0). At pH 9.0 and 37 or 70 degrees C, a significant loss of EC1 wa