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Both the Dimerization and Immunochemical Properties of E-Cadherin EC1 Domain Depend on Trp156 Residue

✍ Scribed by Oscar Y. Laur; Jörg Klingelhöfer; Regina B. Troyanovsky; Sergey M. Troyanovsky


Book ID
115569158
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
316 KB
Volume
400
Category
Article
ISSN
0003-9861

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The objective of this work was to evaluate the solution stability of the EC1 domain of E-cadherin under various conditions. The EC1 domain was incubated at various temperatures (4, 37, and 70 degrees C) and pH values (3.0, 7.0, and 9.0). At pH 9.0 and 37 or 70 degrees C, a significant loss of EC1 wa