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Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

✍ Scribed by Hayashi, Hironori; Ichihara, Masatoshi; Iwashita, Toshihide; Murakami, Hideki; Shimono, Yohei; Kawai, Kumi; Kurokawa, Kei; Murakumo, Yoshiki; Imai, Tsuneo; Funahashi, Hiroomi

Book ID
110064115
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
217 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN