## Abstract Serum immune complexes were measured in 92 patients with progressive systemic sclerosis, and elevated levels were found as follows: Raji cell assay 72% (59% after pronase treatment of Raji cells), agarose gel electrophoresis 52%, and C1q binding 24%. Fortythree (47%) had abnormal result
Characterization of immune complexes in progressive rubella panencephalitis
β Scribed by P. K. Coyle; Dr. Jerry S. Wolinsky
- Book ID
- 102706941
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 559 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
In two patients with the slow virus disease progressive rubella panencephalitis, high levels of immune complexes were found in serum and, in one case, spinal fluid. These complexes contained immunoglobulin G. Serum complexes sedimented over a wide density range compared with the more homogeneous spinal fluid complexes. Complexes from both serum and spinal fluid contained antibody directed against rubella virus. Serum complexes were also shown to contain rubella antigen (or antigens) that appeared to differ between the two patients.
π SIMILAR VOLUMES
## Abstract Fortyβone patients with progressive systemic sclerosis were studied for the presence of immune complexes by the fluidβ and solidβphase C1q binding, C1 activation, and the fluidβphase conglutinin assays. Complement activation and autoantibodies were also studied. Immune complexes were de
Serum and cerebrospinal fluid were obtained from a 6-year-old male with subacute sclerosing panencephalitis (SSPE). Specimens were collected over a 9-month period beginning in the unusually acute phase and ending in a more quiescent phase of the disease. Immune complexes, auto-antibodies and viral a
## Abstract The hemolysisβinβgel (HIG) technique was adapted for rubella antibody determinations. Use of sucrose gradient purified virus and its coupling with CrCl~3~ to chicken erythrocytes resulted in gel plates that could be stored for several weeks and were suitable for reproducible antibody de